Tumor growth inhibition model

comparison of 2 dosage regimens

dosage regimen 1

Number of doses:

Interdose interval:

Amount:

dosage regimen 2

Number of doses:

Interdose interval:

Amount:

parameters

GAMMA:

KDE:

LAMBDAP:

DELTAQP:

KPQ:

KQPP:

id

time range

grid size

line size

  [LONGITUDINAL]  
  input={K, KDE, KPQ, KQPP, LAMBDAP, GAMMA, DELTAQP}
  
  PK:
  depot(target=C)
  
  EQUATION:
  PT_0=5
  Q_0 = 40
  PSTAR = PT+Q+QP
  ddt_C = -KDE*C
  ddt_PT = LAMBDAP*PT*(1-PSTAR/K) + KQPP*QP - KPQ*PT - GAMMA*KDE*PT*C
  ddt_Q = KPQ*PT - GAMMA*KDE*Q*C
  ddt_QP = GAMMA*KDE*Q*C - KQPP*QP - DELTAQP*QP

Tumor growth inhibition model comparison of 2 dosage regimens

dosage regimen 1

dosage regimen 2

parameters

id

Tumor growth inhibition model

comparison of 2 dosage regimens